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1

Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation §

Geschwindner, Stefan, Olsson, Lise-Lotte, Albert, Jeffrey S., Deinum, Johanna, Edwards, Philip D., de Beer, Tonny, Folmer, Rutger H. A.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 244 KB

english, 2007

2

10.1038/35083007

Cheever, Matthew L., Sato, Trey K., de Beer, Tonny, Kutateladze, Tatiana G., Emr, Scott D., Overduin, Michael

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 1.33 MB

english, 2001

3

10.1038/35083000

Cheever, Matthew L., Sato, Trey K., de Beer, Tonny, Kutateladze, Tatiana G., Emr, Scott D., Overduin, Michael

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 1.34 MB

english, 2001

4

10.1038/74015

Overduin, Michael, de Beer, Tonny

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 279 KB

english, 2000

5

10.1038/80924

de Beer, Tonny, Hoofnagle, Andrew N., Enmon, Jennifer L., Bowers, Rebecca C., Yamabhai, Montarop, Kay, Brian K., Overduin, Michael

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 535 KB

english, 2000

6

Letter to the Editor: Assignment of the 1H, 13C, and 15N resonances of the DNA binding domain of gpNu1, a genome packaging protein from bacteriophage λ

Tonny de Beer, Marcos Ortega, Nancy Berton, Qin Yang, Michael Overduin, Carlos Enrique Catalano

Journal:

Journal of Biomolecular NMR

Year:

2000

Language:

english

File:

PDF, 32 KB

english, 2000

7

Letter to the Editor: Sequence-specific 1H, 15N and 13C resonance assignments for the third EH domain of Eps15

Jennifer L. Enmon, Tonny de Beer, Michael Overduin

Journal:

Journal of Biomolecular NMR

Year:

2000

Language:

english

File:

PDF, 31 KB

english, 2000

8

Solution structure of the α-subunit of human chorionic gonadotropin

Paul J. A. Erbel, Yasmin Karimi-Nejad, Tonny De Beer, Rolf Boelens, Johannis P. Kamerling, Johannes F. G. Vliegenthart

Journal:

Year:

1999

Language:

english

File:

PDF, 1.42 MB

english, 1999

9

Site-Specific and Complete Enzymic Deglycosylation of the Native Human Chorionic Gonadotropin α-Subunit

Carol W. E. M. Van Zuylen, Tonny De Beer, Geert Jan Rademaker, Johan Haverkamp, Jane E. Thomas-Oates, Karl Hård, Johannis P. Kamerling, Johannes F. G. Vliegenthart

Journal:

Year:

1995

Language:

english

File:

PDF, 846 KB

english, 1995

10

NMR Studies of the Free α Subunit of Human Chorionic Gonadotropin : Structural Influences of N-Glycosylation and the β Subunit on the Conformation of the α Subunit

Tonny De Beer, Carol W. E. M. Van Zuylen, Bas R. Leeflang, Karl Hård, Rolf Boelens, Robert Kaptein, Johannis P. Kamerling, Johannes F. G. Vliegenthart

Journal:

Year:

1996

Language:

english

File:

PDF, 1.74 MB

english, 1996

11

Polydispersity in Sulfation Profile of Oligosaccharide Alditols Isolated from the Protein-Linkage Region and the Repeating Disaccharide Region of Chondroitin 4-Sulfate of Bovine Nasal Septal Cartilage

Tonny De Beer, Atsuko Inui, Hiromi Tsuda, Kazuyuki Sugahara, Johannes F. G. Vliegenthart

Journal:

Year:

1996

Language:

english

File:

PDF, 1.02 MB

english, 1996

12

Rapid and simple approach for the NMR resonance assignment of the carbohydrate chains of an intact glycoprotein Application of gradient-enhanced natural abundance 1H-13C HSQC and HSQC-TOCSY to the α-subunit of human chorionic gonadotropin

Tonny de Beer, Carol W.E.M. van Zuylen, Karl Hård, Rolf Boelens, Robert Kaptein, Johannis P. Kamerling, Johannes F.G. Vliegenthart

Journal:

Year:

1994

Language:

english

File:

PDF, 655 KB

english, 1994

13

Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain

Tatiana G Kutateladze, Kenyon D Ogburn, William T Watson, Tonny de Beer, Scott D Emr, Christopher G Burd, Michael Overduin

Journal:

Year:

1999

Language:

english

File:

PDF, 380 KB

english, 1999

14

Insights into Specific DNA Recognition during the Assembly of a Viral Genome Packaging Machine

Tonny de Beer, Jenny Fang, Marcos Ortega, Qin Yang, Levi Maes, Carol Duffy, Nancy Berton, Jean Sippy, Michael Overduin, Michael Feiss, Carlos Enrique Catalano

Journal:

Year:

2002

Language:

english

File:

PDF, 606 KB

english, 2002

15

Mobilities of the Inner Three Core Residues and the Man(α1→6) Branch of the Glycan at Asn78 of the α-Subunit of Human Chorionic Gonadotropin Are Restricted by the Protein †

Thijssen-van Zuylen, Carol W. E. M., de Beer, Tonny, Leeflang, Bas R., Boelens, Rolf, Kaptein, Robert, Kamerling, Johannis P., Vliegenthart, Johannes F. G.

Journal:

Year:

1998

Language:

english

File:

PDF, 126 KB

english, 1998

16

New type of linkage between a carbohydrate and a protein: C-glycosylation of a specific tryptophan residue in human RNase Us

Hofsteenge, Jan, Mueller, Dieter R., de Beer, Tonny, Loeffler, Andreas, Richter, Wilhelm J., Vliegenthart, Johannes F. G.

Journal:

Year:

1994

Language:

english

File:

PDF, 782 KB

english, 1994

17

Cloning, Expression, and Characterization of a DNA Binding Domain of gpNu1, a Phage λ DNA Packaging Protein †

Yang, Qin, de Beer, Tonny, Woods, Liping, Meyer, Jeffrey D., Manning, Mark C., Overduin, Michael, Catalano, Carlos Enrique

Journal:

Year:

1999

Language:

english

File:

PDF, 229 KB

english, 1999

18

The Hexopyranosyl Residue That Is C-Glycosidically Linked to the Side Chain of Tryptophan-7 in Human RNase Us Is .alpha.-Mannopyranose

de Beer, Tonny, Vliegenthart, Johannes F. G., Loeffler, Andreas, Hofsteenge, Jan

Journal:

Year:

1995

Language:

english

File:

PDF, 554 KB

english, 1995

19

Spectroscopic and Protein Chemical Analyses Demonstrate the Presence of C-Mannosylated Tryptophan in Intact Human RNase 2 and Its Isoforms †

Löffler, Andreas, Doucey, Marie-Agnès, Jansson, Anita M., Müller, Dieter R., de Beer, Tonny, Hess, Daniel, Meldal, Morten, Richter, Wilhelm J., Vliegenthart, Johannes F. G., Hofsteenge, Jan

Journal:

Year:

1996

Language:

english

File:

PDF, 527 KB

english, 1996

20

Solution Structure of Eps15's Third EH Domain Reveals Coincident Phe−Trp and Asn−Pro−Phe Binding Sites †,‡

Enmon, Jennifer L., de Beer, Tonny, Overduin, Michael

Journal:

Year:

2000

Language:

english

File:

PDF, 992 KB

english, 2000